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By replacing defective DNA with a genome free of harmful mutations, the researchers—a group of experts from the University of Oregon—were able to produce an egg that generated normal embryos up to five days old and normal embryonic stem cells.
Mitochondrial DNA is always inherited from the mother and transmits incurable genetic diseases that particularly affect the organs and tissues with the highest energy demands.
Experts believe this could pave the way for gene therapies that prevent the onset of maternally inherited diseases.